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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
39.09
Human Site:
Y122
Identified Species:
61.43
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
Y122
P
V
F
F
R
E
E
Y
M
L
N
N
A
V
G
Chimpanzee
Pan troglodytes
XP_515988
440
48807
Y176
P
V
F
F
R
E
E
Y
M
L
N
N
A
V
G
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
Y180
P
V
F
F
R
E
E
Y
M
L
N
N
A
V
G
Dog
Lupus familis
XP_848689
359
39946
C104
L
N
N
A
I
D
C
C
R
K
P
Y
V
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
Y121
Q
D
L
F
R
E
E
Y
I
L
N
N
A
I
A
Rat
Rattus norvegicus
Q5XIE6
385
43006
Y121
Q
D
L
F
R
E
E
Y
I
L
N
N
A
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
Y121
R
D
Y
F
R
E
E
Y
R
L
D
N
A
I
G
Frog
Xenopus laevis
A2VDC2
385
42348
Y121
Q
D
F
F
R
E
E
Y
I
L
N
N
A
I
G
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
Y118
Q
V
F
F
R
E
E
Y
I
L
N
N
T
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
Y126
K
S
F
F
R
E
E
Y
S
T
N
A
L
I
G
Honey Bee
Apis mellifera
XP_396249
396
44074
Y127
E
I
F
L
K
K
E
Y
T
L
N
H
L
I
G
Nematode Worm
Caenorhab. elegans
P34559
288
31153
M33
F
S
S
K
A
P
E
M
I
K
I
E
K
V
G
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
Y115
G
E
F
F
K
N
E
Y
I
L
N
H
T
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
L119
V
M
G
G
G
A
G
L
S
T
N
G
R
F
R
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
Y125
I
K
F
F
T
D
E
Y
S
L
N
F
Q
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
0
N.A.
60
60
N.A.
N.A.
60
73.3
73.3
N.A.
53.3
40
20
46.6
P-Site Similarity:
100
100
100
6.6
N.A.
73.3
73.3
N.A.
N.A.
80
86.6
86.6
N.A.
60
73.3
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
7
0
0
0
0
0
7
47
7
20
% A
% Cys:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% C
% Asp:
0
27
0
0
0
14
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
7
0
0
0
60
87
0
0
0
0
7
0
0
0
% E
% Phe:
7
0
60
74
0
0
0
0
0
0
0
7
0
7
0
% F
% Gly:
7
0
7
7
7
0
7
0
0
0
0
7
0
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
7
7
0
0
7
0
0
0
40
0
7
0
0
60
0
% I
% Lys:
7
7
0
7
14
7
0
0
0
14
0
0
7
0
0
% K
% Leu:
7
0
14
7
0
0
0
7
0
74
0
0
14
0
7
% L
% Met:
0
7
0
0
0
0
0
7
20
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
7
0
0
0
0
80
54
0
0
0
% N
% Pro:
20
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% P
% Gln:
27
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
7
0
0
0
60
0
0
0
14
0
0
0
7
0
7
% R
% Ser:
0
14
7
0
0
0
0
0
20
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
7
14
0
0
14
0
0
% T
% Val:
7
27
0
0
0
0
0
0
0
0
0
0
7
27
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
80
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _